Co-Publication Network

Publications

Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8+ T cell immunity

M. Rosás-Umbert, J.D. Gunst, M.H. Pahus, R. Olesen, M. Schleimann, P.W. Denton, V. Ramos, A. Ward, N.N. Kinloch, D.C. Copertino, T. Escribà, A. Llano, Z.L. Brumme, R. Brad Jones, B. Mothe, C. Brander, J. Fox, M.C. Nussenzweig, S. Fidler, M. Caskey, M. Tolstrup, O.S. Søgaard

View: Nature Communications

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy

A. Shahid, B.R. Jones, J.S.W. Yang, W. Dong, T. Shaipanich, K. Donohoe, C.J. Brumme, J.B. Joy, J.M. Leung, Z.L. Brumme

View: PLoS Pathogens

Prolonged viral suppression with anti-HIV-1 antibody therapy

C. Gaebler, L. Nogueira, E. Stoffel, T.Y. Oliveira, G. Breton, K.G. Millard, M. Turroja, A. Butler, V. Ramos, M.S. Seaman, J.D. Reeves, C.J. Petroupoulos, I. Shimeliovich, A. Gazumyan, C.S. Jiang, N. Jilg, J.F. Scheid, R. Gandhi, B.D. Walker, M.C. Sneller, A. Fauci, T.-W. Chun, M. Caskey, M.C. Nussenzweig

View: Nature

Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial

J.D. Gunst, M.H. Pahus, M. Rosás-Umbert, I.-N. Lu, T. Benfield, H. Nielsen, I.S. Johansen, R. Mohey, L. Østergaard, V. Klastrup, M. Khan, M.H. Schleimann, R. Olesen, H. Støvring, P.W. Denton, N.N. Kinloch, D.C. Copertino, A.R. Ward, W.D.C. Alberto, S.D. Nielsen, M.C. Puertas, V. Ramos, J.D. Reeves, C.J. Petropoulos, J. Martinez-Picado, Z.L. Brumme, R.B. Jones, J. Fox, M. Tolstrup, M.C. Nussenzweig, M. Caskey, S. Fidler, O.S. Søgaard

View: Nature Medicine

Bayesian sampling of HIV-1 integration dates by root-to-tip regression

R.-C. Ferreira, E. Wong, A.F.Y. Poon

View: Virus Evolution

Interferon opens up: HIV-induced inflammation reconfigures 3D chromatin conformation and affects where HIV integrates

Y. Wei, Y.-C. Ho

View: Molecular Cell

HIV-1 replication and latency are balanced by mTOR-driven cell metabolism

J.M. Crater, D.F. Nixon, R.L. Furler O’Brien

View: Frontiers in Cellular and Infection Microbiology

Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen

Pedersen, Savannah F; Collora, Jack A; Kim, Rachel N; Yang, Kerui; Razmi, Anya; Catalano, Allison A; Yeh, Yang-Hui Jimmy; Mounzer, Karam; Tebas, Pablo; Montaner, Luis J; Ho, Ya-Chi.

View: Journal of Virology

No evidence that circulating HIV-specific immune responses contribute to persistent inflammation and immune activation in persons on long-term ART

Ward, Adam R; Thomas, Allison S; Stevenson, Eva M; Huang, Szu-Han; Keating, Sheila M; Gandhi, Rajesh T; McMahon, Deborah K; Bosch, Ronald J; Macatangay, Bernard J; Cyktor, Joshua C; Eron, Joseph J; Mellors, John W; Jones, R Brad; ACTG A5321 Team.

View: AIDS

The loud minority: Transcriptionally active HIV-1-infected cells survive, proliferate, and persist

Collora, Jack A; Ho, Ya-Chi.

View: Cell

Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins

Zhang, Fengwen; Zang, Trinity M; Stevenson, Eva M; Lei, Xiao; Copertino, Dennis C; Mota, Talia M; Boucau, Julie; Garcia-Beltran, Wilfredo F; Jones, R Brad; Bieniasz, Paul D.

View: PNAS

SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells

Stevenson, Eva M; Terry, Sandra; Copertino, Dennis; Leyre, Louise; Danesh, Ali; Weiler, Jared; Ward, Adam R; Khadka, Pragya; McNeil, Evan; Bernard, Kevin; Miller, Itzayana G; Ellsworth, Grant B; Johnston, Carrie D; Finkelsztein, Eli J; Zumbo, Paul; Betel, Doron; Dündar, Friederike; Duncan, Maggie C; Lapointe, Hope R; Speckmaier, Sarah; Moran-Garcia, Nadia; Papa, Michelle Premazzi; Nicholes, Samuel; Stover, Carissa J; Lynch, Rebecca M; Caskey, Marina; Gaebler, Christian; Chun, Tae-Wook; Bosque, Alberto; Wilkin, Timothy J; Lee, Guinevere Q; Brumme, Zabrina L; Jones, R Brad.

View: Nature Communications

Potential multi-modal effects of provirus integration on HIV-1 persistence: lessons from other viruses

Linden, Noemi; Jones, R Brad.

View: Trends in Immunology

Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses

Weymar, Georg H J; Bar-On, Yotam; Oliveira, Thiago Y; Gaebler, Christian; Ramos, Victor; Hartweger, Harald; Breton, Gaëlle; Caskey, Marina; Cohn, Lillian B; Jankovic, Mila; Nussenzweig, Michel C.

View: Cell Reports

Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing

Cho, Alice; Gaebler, Christian; Olveira, Thiago; Ramos, Victor; Saad, Marwa; Lorenzi, Julio C C; Gazumyan, Anna; Moir, Susan; Caskey, Marina; Chun, Tae-Wook; Nussenzweig, Michel C.

View: PNAS

Hide and seek: for HIV-infected CD4+ T cells, playing well comes with maturity

Leyre, Louise; Jones, R Brad.

View: Journal of Clinical Investigation

Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones

Collora, Jack A; Liu, Runxia; Pinto-Santini, Delia; Ravindra, Neal; Ganoza, Carmela; Lama, Javier R; Alfaro, Ricardo; Chiarella, Jennifer; Spudich, Serena; Mounzer, Karam; Tebas, Pablo; Montaner, Luis J; van Dijk, David; Duerr, Ann; Ho, Ya-Chi.

View: Immunity

Deep Sequencing Analysis of Individual HIV-1 Proviruses Reveals Frequent Asymmetric Long Terminal Repeats

Joseph, Kevin W; Halvas, Elias K; Brandt, Leah D; Patro, Sean C; Rausch, Jason W; Chopra, Abha; Mallal, Simon; Kearney, Mary F; Coffin, John M; Mellors, John W.

View: Journal of Virology

HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy

Omondi, F Harrison; Sudderuddin, Hanwei; Shahid, Aniqa; Kinloch, Natalie N; Jones, Bradley R; Miller, Rachel L; Tsai, Olivia; MacMillan, Daniel; Trocha, Alicja; Brockman, Mark A; Brumme, Chanson J; Joy, Jeffrey B; Liang, Richard; Walker, Bruce D; Brumme, Zabrina L.

View: mBio

Integration features of intact latent HIV-1 in CD4+ T cell clones contribute to viral persistence

Huang, Amy S; Ramos, Victor; Oliveira, Thiago Y; Gaebler, Christian; Jankovic, Mila; Nussenzweig, Michel C; Cohn, Lillian B.

View: Journal of Experimental Medicine